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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D23
All Species:
27.58
Human Site:
S252
Identified Species:
55.15
UniProt:
Q9NUY8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUY8
NP_060779.2
699
78322
S252
I
L
T
Q
E
S
D
S
K
E
E
V
I
K
F
Chimpanzee
Pan troglodytes
XP_001142898
699
78360
S252
I
L
T
Q
E
S
D
S
K
E
E
V
I
Q
F
Rhesus Macaque
Macaca mulatta
XP_001089575
699
78401
S252
I
L
T
Q
E
S
D
S
K
E
E
V
I
Q
F
Dog
Lupus familis
XP_535717
699
78459
S252
I
L
A
Q
E
S
D
S
K
E
E
V
I
Q
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0F1
684
76407
S252
I
L
A
Q
E
S
D
S
K
E
E
V
I
R
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518998
1159
128900
S725
I
L
A
Q
E
S
D
S
K
E
E
I
I
E
F
Chicken
Gallus gallus
Q5F415
679
75993
E245
V
I
L
A
Q
E
S
E
K
E
E
M
L
K
F
Frog
Xenopus laevis
Q6NRC7
682
76832
D237
V
L
G
Q
D
M
D
D
K
E
E
L
I
K
C
Zebra Danio
Brachydanio rerio
Q7SXV1
680
76081
N248
I
L
I
Q
E
G
D
N
K
E
E
I
I
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608569
689
77454
S239
I
L
Q
M
R
S
S
S
K
E
E
I
I
K
F
Honey Bee
Apis mellifera
XP_624741
648
73025
L222
D
P
F
F
M
L
F
L
S
L
I
M
V
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788039
808
91017
S282
I
M
G
M
T
E
S
S
R
D
E
L
I
D
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.1
96.4
N.A.
92.1
N.A.
N.A.
54.6
87.1
80.2
75.2
N.A.
44.9
41.3
N.A.
38.3
Protein Similarity:
100
99.4
99.1
98
N.A.
95.8
N.A.
N.A.
56.9
92.5
88.2
84.8
N.A.
61.7
59.7
N.A.
55
P-Site Identity:
100
93.3
93.3
86.6
N.A.
86.6
N.A.
N.A.
80
33.3
53.3
66.6
N.A.
66.6
0
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
N.A.
N.A.
93.3
66.6
73.3
80
N.A.
73.3
13.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
9
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% C
% Asp:
9
0
0
0
9
0
67
9
0
9
0
0
0
9
0
% D
% Glu:
0
0
0
0
59
17
0
9
0
84
92
0
0
9
0
% E
% Phe:
0
0
9
9
0
0
9
0
0
0
0
0
0
0
67
% F
% Gly:
0
0
17
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
75
9
9
0
0
0
0
0
0
0
9
25
84
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
84
0
0
0
0
42
0
% K
% Leu:
0
75
9
0
0
9
0
9
0
9
0
17
9
0
0
% L
% Met:
0
9
0
17
9
9
0
0
0
0
0
17
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
67
9
0
0
0
0
0
0
0
0
25
0
% Q
% Arg:
0
0
0
0
9
0
0
0
9
0
0
0
0
9
0
% R
% Ser:
0
0
0
0
0
59
25
67
9
0
0
0
0
0
0
% S
% Thr:
0
0
25
0
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
17
0
0
0
0
0
0
0
0
0
0
42
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _